Cart
sales@molnova.com
Home - Products - Angiogenesis - Bcl-2 - trans-Ferulic acid

trans-Ferulic acid

CAS No. 537-98-4

trans-Ferulic acid ( (E)-Coniferic acid )

Catalog No. M20346 CAS No. 537-98-4

Trans-Ferulic acid causes the phosphorylation of β-catenin resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin.trans-Ferulic acid exert both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG 37 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    trans-Ferulic acid
  • Note
    Research use only not for human use.
  • Brief Description
    Trans-Ferulic acid causes the phosphorylation of β-catenin resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin.trans-Ferulic acid exert both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.
  • Description
    Trans-Ferulic acid causes the phosphorylation of β-catenin resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin.trans-Ferulic acid exert both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.
  • Synonyms
    (E)-Coniferic acid
  • Pathway
    Angiogenesis
  • Target
    Bcl-2
  • Recptor
    Bax
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    537-98-4
  • Formula Weight
    194.18
  • Molecular Formula
    C10H10O4?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1cc(\C=C\C(O)=O)ccc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fong Y Tang C C Hu H T et al. Inhibitory effect oftrans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability[J]. Chinese Medicine 2016 11(1):45.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • BXI-72

    BXI-72 (NSC334072, Hoechst 33342) is a potent, selective small molecule Bcl-XL inhibitor that targets the BH3 domain of Bcl-XL (Kd=0.9 nM).

  • Allethrin

    Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.

  • Apogossypol

    Apogossypol (NSC 736630) is a Bcl-2 family antagonist that binds to Bcl-XL, Bcl-2 and Bcl-xL with IC50 of 2.6, 2.8 and 3.69 uM, respectively.

Sign In Join Free