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trans-Ferulic acid

CAS No. 537-98-4

trans-Ferulic acid ( (E)-Coniferic acid )

Catalog No. M20346 CAS No. 537-98-4

Trans-Ferulic acid causes the phosphorylation of β-catenin resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin.trans-Ferulic acid exert both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    trans-Ferulic acid
  • Note
    Research use only not for human use.
  • Brief Description
    Trans-Ferulic acid causes the phosphorylation of β-catenin resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin.trans-Ferulic acid exert both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.
  • Description
    Trans-Ferulic acid causes the phosphorylation of β-catenin resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin.trans-Ferulic acid exert both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.
  • Synonyms
    (E)-Coniferic acid
  • Pathway
    Angiogenesis
  • Target
    Bcl-2
  • Recptor
    Bax
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    537-98-4
  • Formula Weight
    194.18
  • Molecular Formula
    C10H10O4?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1cc(\C=C\C(O)=O)ccc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fong Y Tang C C Hu H T et al. Inhibitory effect oftrans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability[J]. Chinese Medicine 2016 11(1):45.
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